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Start your consultation on the condition page to check your eligibility. The price includes a medical consultation with a qualified doctor and, where appropriate, a prescription for medication.

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Why choose weight loss medication?

GLP-1 receptor agonists are changing the way weight loss is approached. Originally developed to support people with type 2 diabetes, these medications are now widely recognised for their effectiveness in weight management.

GLP-1 weight loss treatments work by mimicking natural hormones that help regulate appetite, slow digestion, and increase feelings of fullness. This makes it easier to reduce calorie intake and supports sustainable, long-term weight loss.

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Clinically proven weight loss treatments

Proven results, backed by science

Medications targeting GLP-1 receptors offer clinically proven results for people living with obesity or weight-related health conditions. These treatments are not quick fixes. They form part of a longer-term medical approach designed to support a healthier lifestyle.

By reducing hunger signals and increasing feelings of fullness, GLP-1 therapies can help patients lose a meaningful percentage of their body weight when combined with appropriate lifestyle changes.

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Product details

Medication type

Hormone replacement therapy (HRT) containing estradiol, a natural oestrogen.

Active ingredient

Estradiol

Generic

Yes

Side effects

Breast tenderness, bloating, nausea, headaches, mood changes, or light vaginal bleeding may occur.
Less commonly: fluid retention, skin rashes, weight gain, or irritation at the application site.
Contact a doctor immediately if you experience chest pain, shortness of breath, jaundice, or sudden swelling of the legs.

Works within

Oestrogel contains estradiol, an oestrogen identical to that naturally produced by the ovaries. It works by restoring oestrogen levels in postmenopausal women, helping to relieve symptoms related to hormonal deficiency such as hot flushes, night sweats, vaginal dryness, and sleep disturbances.

Effective in

You may notice an improvement in symptoms within the first few weeks, but it typically takes 8 to 12 weeks of consistent use to fully rejuvenate the vaginal lining and eliminate dryness or pain.

FAQs

Veuillez consulter notre page FAQ pour en savoir plus.

Does this medication enter my bloodstream?

Vagifem is a "local" treatment. While a tiny amount of oestrogen may be absorbed, the vast majority stays in the vaginal tissue where it is needed. This is why it is considered safer than tablets or patches for women who only have vaginal symptoms.

Can I have sex while using this?

Yes. Vagifem helps restore lubrication and elasticity, making intercourse more comfortable. It is best to insert the tablet after sexual activity (before going to sleep) so that it stays in place overnight.

Is there a difference between Vagifem and Vagirux?

Only in branding and packaging. Vagifem is the original brand by Novo Nordisk, while Vagirux is a generic version. Both contain the exact same active ingredient (10mcg estradiol) and work in the same way. Some women prefer Vagifem for its specific applicator design or simply because they are used to the brand.

Do I need to take Progesterone with this?

Generally, No. Because the dose is local and very low, it usually does not affect the lining of the womb. Therefore, most doctors do not require you to take additional progesterone (like Utrogestan) if you are only using Vagifem.

Is the applicator reusable?

No. One of the key benefits of Vagifem is that each tablet comes in its own sterile, disposable applicator. You use it once to insert the tablet and then throw the plastic applicator away. This ensures maximum hygiene.

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